AH
4,914 Studies

Photobiomodulation Research

The science of light therapy. Peer-reviewed research on how specific wavelengths of red and near-infrared light affect cellular function, healing, and performance.

1,572
Human Studies
1,865
Animal Studies
820
In Vitro
617
Reviews

Research Synthesis

Key findings from 4,914 peer-reviewed studies on photobiomodulation therapy.

Mitochondrial ATP Production

Red and near-infrared light activates cytochrome c oxidase in mitochondria, increasing ATP production by 20-50% in treated cells.

Reduced Inflammation

PBM decreases pro-inflammatory cytokines (IL-1β, IL-6, TNF-α) and increases anti-inflammatory mediators.

Accelerated Wound Healing

345+ studies show PBM speeds wound closure, increases collagen synthesis, and improves tissue regeneration.

Neurological Benefits

243 brain studies demonstrate improved cognitive function, reduced neuroinflammation, and neuroprotection.

Bone Regeneration

PBM accelerates fracture healing, increases osteoblast activity, and improves bone mineral density.

Eye Health

104 studies on retinal protection, macular degeneration, and vision improvement through targeted light therapy.

Top Research Categories

Oral

974

studies

Wound healing

345

studies

Bone

276

studies

Muscle

258

studies

Pain

249

studies

Brain

243

studies

Explore by Condition

Detailed breakdowns with study-level data, methodology stats, and wavelength analysis.

The Biphasic Dose Response

PBM follows an Arndt-Schulz curve: too little light has no effect, optimal doses stimulate beneficial responses, and too much can inhibit or cause harm. This is why device specs should match research protocols.

Power Density

10-100 mW/cm²

Energy Density

1-50 J/cm²

Treatment Time

30s - 20 min

Frequency

Daily to 3x/week