PBM Research167 studies

Photobiomodulation for Cells

167 peer-reviewed studies on light therapy for cells, spanning 1984 to 2020. Filtered from the full PBM database of 4,914 studies.

167

Total Studies

Human Studies

154

Positive Results

Wavelength Bands

Study Types

In vitro

154 (92%)

Review

8 (5%)

Mouse

2 (1%)

Human

2 (1%)

Rat

1 (1%)

Outcomes

positive

154 (92%)

unclear

10 (6%)

negative

3 (2%)

Wavelength Distribution

Red (600-700nm)

71 studies

Not specified

60 studies

Near-IR (700-900nm)

21 studies

IR (900nm+)

15 studies

All Studies (167)

Biphasic Dose/Response of Photobiomodulation Therapy on Culture of Human Fibroblasts.

Flores LunaPhotobiomodul Photomed Laser Surg2020660nm

positiveIn vitro

RNA-Seq analysis revealed the molecular mechanisms of photobiomodulation effect on human fibroblasts.

LiPhotodermatol Photoimmunol Photomed2020

positiveIn vitro

Photobiomodulation with 630-nm LED radiation inhibits the proliferation of human synoviocyte MH7A cells possibly via TRPV4/PI3K/AKT/mTOR signaling pathway.

MengLasers Med Sci2020630nm

positiveIn vitro

A Comprehensive Analysis of Near‐Contact Photobiomodulation Therapy in the Host–Bacteria Interaction Model Using 3D‐Printed Modular LED Platform

KimAdv Biosyst2020

positiveIn vitro

Beyond 2D: effects of photobiomodulation in 3D tissue-like systems.

BikmulinaJ Biomed Opt2020

positiveIn vitro

Photobiomodulation alters the viability of HUVECs cells.

TerenaLasers Med Sci2020

positiveIn vitro

Fluorescent Light Energy (FLE) Acts on Mitochondrial Physiology Improving Wound Healing.

FerroniJ Clin Med2020

positiveIn vitro

Photobiomodulation and the expression of genes related to the JAK/STAT signalling pathway in wounded and diabetic wounded cells.

JereJ Photochem Photobiol B2020660nm

positiveIn vitro

Activation of the extracellular signal-regulated kinase signal pathway by light emitting diode irradiation.

KomineLasers Med Sci2020627nm

positiveIn vitro

Photobiomodulation can alter mRNA levels cell death-related.

da SilvaLasers Med Sci2019830nm

positiveMouse

Effects of photobiomodulation on mitochondria of brain, muscle, and C6 astroglioma cells.

SilveiraMed Eng Phys2019660nm

positiveIn vitro

Photobiomodulation at 660 nm Stimulates Fibroblast Differentiation.

MokoenaLasers Med Sci2019660nm

positiveIn vitro

Human Fibroblast Gene Expression Modulation Using 940 NM Diode Laser.

Illescas-MontesSci Rep2019940nm

positiveIn vitro

Photobiomodulation therapy can change actin filaments of 3T3 mouse fibroblast.

de MagalhãesLasers Med Sci2019

positiveIn vitro

Effect of Photobiomodulation on Secretion of IL-6 and IL-8 by Human Gingival Fibroblasts In Vitro.

HarorliPhotobiomodul Photomed Laser Surg2019940nm

positiveIn vitro

Interaction between low-level laser therapy and Guarana (Paullinia cupana) extract induces antioxidant, anti-inflammatory, and anti-apoptotic effects and promotes proliferation in dermal fibroblasts.

MaldanerJ Cosmet Dermatol2019660nm

positiveIn vitro

In vitro effect of low-level laser therapy on the proliferative, apoptosis modulation, and oxi-inflammatory markers of premature-senescent hydrogen peroxide-induced dermal fibroblasts.

MaldanerLasers Med Sci2019660nm

negativeIn vitro

Light-emitting diode irradiation using 660 nm promotes human fibroblast HSP90 expression and changes cellular activity and morphology.

ChoiJ Biophotonics2019660nm

positiveIn vitro

Combined treatment of low-level laser therapy and phloroglucinol for inhibition of fibrosis.

LeeLasers Surg Med2019635nm

positiveIn vitro

Photobiomodulation effects on keratinocytes cultured in vitro: a critical review

de AbreuLasers Med Sci2019

unclearReview

Protective effect of Photobiomodulation Therapy and Bone Marrow Stromal Stem Cells Conditioned Media on Pheochromocytoma Cell Line 12 Against Oxidative Stress Induced by Hydrogen Peroxide.

KhoshsiratJ Lasers Med Sci2019633nm

positiveIn vitro

Photobiomodulation (660 nm) therapy reduces oxidative stress and induces BDNF expression in the hippocampus.

HeoSci Rep2019660nm

positiveIn vitro

Photobiomodulation increases cell viability via AKT activation in an in vitro model of diabetes induced by glucose neurotoxicity.

da Silva OliveiraLasers Med Sci2019660nm

positiveIn vitro

Low-level laser therapy alleviates the deleterious effect of doxorubicin on rat adipose tissue-derived mesenchymal stem cells.

de LimaJ Photochem Photobiol B2019660nm

positiveIn vitro

Effect of photobiomodulation therapy on neuronal injuries by ouabain: the regulation of Na, K-ATPase; Src; and mitogen-activated protein kinase signaling pathway.

RheeBMC Neurosci2019660nm

positiveIn vitro

Cell Adhesion Molecules are Mediated by Photobiomodulation at 660 nm in Diabetic Wounded Fibroblast Cells.

HoureldCells2018660nm

positiveIn vitro

Low power lasers on genomic stability

da Silva Neto Trajano (??)J Photochem Photobiol B2018

unclearReview

Photobiomodulation with 808-nm diode laser light promotes wound healing of human endothelial cells through increased reactive oxygen species production stimulating mitochondrial oxidative phosphorylation.

AmaroliLasers Med Sci2018808nm

positiveIn vitro

Differential response of human dermal fibroblast subpopulations to visible and near-infrared light: Potential of photobiomodulation for addressing cutaneous conditions.

MignonLasers Surg Med2018

positiveIn vitro

The effect of polarized light on the organization of collagen secreted by fibroblasts.

AkilbekovaLasers Med Sci2018800nm

positiveIn vitro

Effect of 660 nm visible red light on cell proliferation and viability in diabetic models in vitro under stressed conditions.

AyukLasers Med Sci2018660nm

positiveIn vitro

Erythrocytic bioactivation of nitrite and its potentiation by far-red light.

WajihRedox Biol2018660nm

positiveRat

Ascorbate attenuates red light mediated vasodilation: Potential role of S-nitrosothiols.

KeszlerRedox Biol2018670nm

positiveIn vitro

Effects of Laser Radiation on Mitochondria and Mitochondrial Proteins Subjected to Nitric Oxide.

OsipovFront Med (Lausanne)2018

unclearReview

Photobiomodulation induces in vitro re-epithelialization via nitric oxide production.

RizziLasers Med Sci2018980nm

positiveIn vitro

Effect of Laser Irradiation on Cell Cycle and Mitosis.

GanjaliJ Lasers Med Sci2018633nm

positiveIn vitro

LED enhances anti-inflammatory effect of luteolin (3',4',5,7-tetrahydroxyflavone) in vitro.

FanAm J Transl Res2018

positiveIn vitro

Effect of red light and near infrared laser on the generation of reactive oxygen species in primary dermal fibroblasts

GeorgeJ Photochem Photobiol B2018

positiveIn vitro

Wound-healing effects of 635-nm low-level laser therapy on primary human vocal fold epithelial cells: an in vitro study.

LouLasers Med Sci2018635nm

positiveIn vitro

Effect of NIR photobiomodulation therapy in a cellular wound healing model.

KönigPhotodermatol Photoimmunol Photomed2018

positiveIn vitro

Photobiomodulation therapy promotes in vitro wound healing in nicastrin KO HaCaT cells.

TricaricoJ Biophotonics2018970nm

positiveIn vitro

Photobiomodulation at 660nm stimulates proliferation and migration of diabetic wounded cells via the expression of epidermal growth factor and the JAK/STAT pathway.

JereJ Photochem Photobiol B2018660nm

positiveIn vitro

Red (660 nm) or near-infrared (810 nm) photobiomodulation stimulates, while blue (415 nm), green (540 nm) light inhibits proliferation in human adipose-derived stem cells.

WangSci Rep2017

positiveIn vitro

Photobiomodulation alters matrix protein activity in stressed fibroblast cells in vitro.

AyukJ Biophotonics2017

positiveIn vitro

The effects of low level laser irradiation on proliferation of human dental pulp: a narrative review.

StaffoliClin Ter2017

unclearReview

The impact of wavelengths of LED light-therapy on endothelial cells.

RohringerSci Rep2017

positiveIn vitro

A Comparative Study of 660 nm Low-Level Laser and Light Emitted Diode in Proliferative Effects of Fibroblast Cells.

NaderiJ Lasers Med Sci2017660nm

positiveIn vitro

Low-level laser irradiation induces in vitro proliferation of stem cells from human exfoliated deciduous teeth.

GinaniLasers Med Sci2017660nm

positiveIn vitro

The Effects of Photobiomodulation Delivered by Light-Emitting Diode on Stem Cells from Human Exfoliated Deciduous Teeth: A Study on the Relevance to Pluripotent Stem Cell Viability and Proliferation.

ValePhotomed Laser Surg2017630nm

positiveIn vitro

LLLT Effects on Oral Keratinocytes in an Organotypic 3D Model.

BassoPhotochem Photobiol2017780nm

positiveIn vitro

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