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PBM Research53 studies

Photobiomodulation for Diabetes mellitus

53 peer-reviewed studies on light therapy for diabetes mellitus, spanning 1998 to 2020. Filtered from the full PBM database of 4,914 studies.

53

Total Studies

23

Human Studies

40

Positive Results

4

Wavelength Bands

Study Types

Human
23 (43%)
Review
11 (21%)
Rat
11 (21%)
Mouse
3 (6%)
In vitro
3 (6%)
Animal
2 (4%)

Outcomes

positive
40 (75%)
unclear
13 (25%)

Wavelength Distribution

Not specified

32 studies

Red (600-700nm)

13 studies

Near-IR (700-900nm)

6 studies

IR (900nm+)

2 studies

All Studies (53)

A Systematic Review and Meta-Analysis of the Effects of Low-Level Laser Therapy in the Treatment of Diabetic Foot Ulcers.

SantosInt J Low Extrem Wounds2020
unclearReview

Combined effects of metformin and photobiomodulation improve the proliferation phase of wound healing in type 2 diabetic rats.

BagheriBiomed Pharmacother2020890nm
positiveRat

At-Home Self-Applied Photobiomodulation Device for the Treatment of Diabetic Foot Ulcers in Adults With Type 2 Diabetes: Report of 4 Cases.

Raizman & GavishCan J Diabetes2020808nm
positiveHuman

The effect of electric field, magnetic field, and infrared ray combination to reduce HOMA-IR index and GLUT 4 in diabetic model of Mus musculus.

SuhariningsihLasers Med Sci2019941nm
positiveMouse

Intravenous Laser Wavelength Irradiation Effect on Interleukins: IL-1α, IL-1β, IL6 in Diabetic Rats.

AmjadiLaser Ther2019
positiveRat

Intravenous laser wavelength radiation effect on LCAT, PON1, catalase, and FRAP in diabetic rats.

AmjadiLasers Med Sci2019
positiveRat

Healing Effects of Photobiomodulation on Diabetic Wounds

Houreld NAppl Sci2019
unclearReview

Combined Adipose-Derived Mesenchymal Stem Cells and Photobiomodulation Could Modulate the Inflammatory Response and Treat Infected Diabetic Foot Ulcers.

Bayat & ChienPhotobiomodul Photomed Laser Surg2019
unclearAnimal

Role of the PI3K/AKT (mTOR and GSK3β) signalling pathway and photobiomodulation in diabetic wound healing.

JereCytokine Growth Factor Rev2019
unclearReview

Comparative study on laser and LED influence on tissue repair and improvement of neuropathic symptoms during the treatment of diabetic ulcers.

VitorianoLasers Med Sci2019
positiveHuman

Regeneration of Diabetic Foot Ulcers Based on Therapy with Red LED Light and a Natural Latex Biomembrane.

RosaAnn Biomed Eng2019
positiveHuman

Efficacy of low level infrared light therapy on wound healing in patients with chronic diabetic foot ulcers: a randomised control trial

SangmaInt Surg J2019
positiveHuman

Low-level laser irradiation modifies the effect of hyperglycemia on adhesion molecule levels.

GóralczykLasers Med Sci2018
positiveIn vitro

A randomized controlled trial comparing helium-neon laser therapy and infrared laser therapy in patients with diabetic foot ulcer.

TantawyLasers Med Sci2018
positiveHuman

Photobiomodulation therapy in neuroischaemic diabetic foot ulcers: a novel method of limb salvage.

MaiyaJ Wound Care2018
positiveHuman

New insights into the treatment of non-healing diabetic foot ulcers

VicentiJ Biol Regul Homeost Agents2018
unclearReview

Efficacy of Low-Level Light Therapy for Treatment of Diabetic Foot Ulcer: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

LiDiabetes Res Clin Pract2018
unclearReview

Phototherapy with LED Shows Promising Results in Healing Chronic Wounds in Diabetes Mellitus Patients: A Prospective Randomized Double-Blind Study.

FrangežPhotomed Laser Surg2018
positiveHuman

Effects of Low-Power Light Therapy on the Tissue Repair Process of Chronic Wounds in Diabetic Feet.

de Alencar Fonseca SantosPhotomed Laser Surg2018660nm
positiveHuman

The effect of combined photobiomodulation and metformin on open skin wound healing in a non-genetic model of type II diabetes.

AsghariJ Photochem Photobiol B2017890nm
positiveRat

Effect of low-level light therapy on diabetic foot ulcers: a near-infrared spectroscopy study.

SalviJ Biomed Opt2017830nm
positiveHuman

Low-power laser irradiation in salivary glands reduces glycemia in streptozotocin-induced diabetic female rats.

FukuokaJ Biophotonics2016660nm
positiveRat

Low-level laser irradiation effect on endothelial cells under conditions of hyperglycemia.

GóralczykLasers Med Sci2016
positiveIn vitro

Modifying effect of intravenous laser therapy on the protein expression of arginase and epidermal growth factor receptor in type 2 diabetic patients.

KazemikhooLasers Med Sci2016630nm
positiveHuman

Low-level Light Therapy for Treatment of Diabetic Foot Ulcer: A Review of Clinical Experiences.

Tchanque-FossuoJ Drugs Dermatol2016
unclearReview

A systematic review of low-level light therapy for treatment of diabetic foot ulcer.

Tchanque-FossuoWound Repair Regen2016
unclearReview

The Role of Matrix Metalloproteinases in Diabetic Wound Healing in relation to Photobiomodulation

AyukJ Diabetes Res2016
unclearReview

Low-level laser therapy and Calendula officinalis in repairing diabetic foot ulcers.

CarvalhoRev Esc Enferm USP2016658nm
positiveHuman

Low-level laser therapy as an adjunct to conventional therapy in the treatment of diabetic foot ulcers.

MathurLasers Med Sci2016660nm
positiveHuman

A pilot study to evaluate the efficacy of class IV lasers on nonhealing neuroischemic diabetic foot ulcers in patients with type 2 diabetes.

MalteseDiabetes Care2015
positiveHuman

Healing of diabetic ulcers using photobiomodulation.

Houreld NNPhotomed Laser Surg2015
unclearAnimal

Effects of the Low-Level Laser Therapy (LLLT) in the process of healing diabetic foot ulcers.

FeitosaActa Cir Bras2015633nm
positiveHuman

Defining a therapeutic window for laser irradiation (810 nm) applied to the inguinal region to ameliorate diabetes in diabetic mice.

Peplow & BaxterLasers Surg Med2014810nm
positiveMouse

The effects of low-level laser irradiation on cellular viability and proliferation of human skin fibroblasts cultured in high glucose mediums.

EsmaeelinejadLasers Med Sci2014633nm
positiveIn vitro

Antihyperglycaemic effect of laser acupuncture treatment at BL20 in diabetic rats.

Cornejo-GarridoAcupunct Med2014
positiveRat

Low level laser therapy for the treatment of diabetic foot ulcers: a critical survey.

BeckmannEvid Based Complement Alternat Med2014
unclearReview

Shedding light on a new treatment for diabetic wound healing: a review on phototherapy.

Houreld NNScientificWorldJournal2014
unclearReview

Testing infrared laser phototherapy (810 nm) to ameliorate diabetes: irradiation on body parts of diabetic mice.

Peplow & BaxterLasers Surg Med2013810nm
positiveMouse

Short-term multimodal phototherapy approach in a diabetic ulcer patient.

ChandrasekaranSingapore Med J2012
positiveHuman

Efficacy of low level laser therapy on wound healing in patients with chronic diabetic foot ulcers-a randomised control trial.

KajagarIndian J Surg2012
positiveHuman

A randomized clinical trial on the effect of low-level laser therapy on chronic diabetic foot wound healing: a preliminary report.

KavianiPhotomed Laser Surg2011685nm
positiveHuman

Visible light-induced healing of diabetic or venous foot ulcers: a placebo-controlled double-blind study.

LandauPhotomed Laser Surg2011
positiveHuman

Phototherapy promotes healing of chronic diabetic leg ulcers that failed to respond to other therapies.

MinatelLasers Surg Med2009
positiveHuman

Photo-stimulatory effect of low energy helium-neon laser irradiation on excisional diabetic wound healing dynamics in Wistar rats.

MaiyaIndian J Dermatol2009633nm
positiveRat

Laser therapy converts diabetic wound healing to normal healing.

Al-Watban FAPhotomed Laser Surg2009
positiveRat

Low-level laser therapy enhances wound healing in diabetic rats: a comparison of different lasers.

Al-WatbanPhotomed Laser Surg2007
positiveRat

Comparison of the photostimulatory effects of visible He-Ne and infrared Ga-As lasers on healing impaired diabetic rat wounds.

Reddy GKLasers Surg Med2003904nm
positiveRat

Polychromatic LED therapy in burn healing of non-diabetic and diabetic rats.

Al-Watban & AndresJ Clin Laser Med Surg2003
positiveRat

Topical hyperbaric oxygen and low energy laser therapy for chronic diabetic foot ulcers resistant to conventional treatment.

Landau & SchattnerYale J Biol Med2001633nm
positiveHuman

Using lasers in diabetic wound healing.

Forney & MauroDiabetes Technol Ther1999
unclearReview
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