PBM Research55 studies

Photobiomodulation for Heart

55 peer-reviewed studies on light therapy for heart, spanning 1988 to 2019. Filtered from the full PBM database of 4,914 studies.

Total Studies

Human Studies

Positive Results

Wavelength Bands

Study Types

Rat

29 (53%)

Human

9 (16%)

Review

5 (9%)

Animal

4 (7%)

In vitro

4 (7%)

Mouse

2 (4%)

Outcomes

positive

48 (87%)

unclear

6 (11%)

negative

1 (2%)

Wavelength Distribution

Red (600-700nm)

20 studies

Not specified

19 studies

Near-IR (700-900nm)

16 studies

All Studies (55)

Noninvasive LED therapy: A novel approach for post-infarction ventricular arrhythmias and neuro-immune modulation.

WangJ Cardiovasc Electrophysiol2019610nm

positiveRat

Light-emitting diode therapy protects against ventricular arrhythmias by neuro-immune modulation in myocardial ischemia and reperfusion rat model.

WangJ Neuroinflammation2019610nm

positiveRat

Acute effect of photobiomodulation using light-emitting diodes (LEDs) on baroreflex sensitivity during and after constant loading exercise in patients with type 2 diabetes mellitus

Milan-MattosLasers Med Sci2019850nm

positiveHuman

Photobiomodulation therapy combined with carvedilol attenuates post-infarction heart failure by suppressing excessive inflammation and oxidative stress in rats.

GrandinettiSci Rep2019830nm

positiveRat

Acute Effects of Low-Level Laser Therapy on Patients' Functional Capacity in the Postoperative Period of Coronary Artery Bypass Graft Surgery: A Randomized, Crossover, Placebo-Controlled Trial.

SteinPhotomed Laser Surg2018850nm

positiveHuman

Low-level light therapy reduces platelet destruction during extracorporeal circulation

DrohomireckaSci Rep2018

negativeAnimal

Surface electromyography after lower level laser therapy application on skeletal muscles in individuals with heart failure.

DelacosteLasers Med Sci2018850nm

positiveHuman

Adjunctive laser-stimulated stem-cells therapy to primary reperfusion in acute myocardial infarction in humans: Safety and feasibility study.

Elbaz-GreenerJ Interv Cardiol2018808nm

positiveHuman

Influence of Low-Intensive Red Light on the Myocardium in Experimental Asphyxia.

BavrinaBull Exp Biol Med2018

positiveRat

A Role for Photobiomodulation in the Prevention of Myocardial Ischemic Reperfusion Injury: A Systematic Review and Potential Molecular Mechanisms.

LiebertSci Rep2017

unclearReview

Effect of low-level laser-treated mesenchymal stem cells on myocardial infarction.

El GammalLasers Med Sci2017

unclearReview

Low-Level Laser Application in the Early Myocardial Infarction Stage Has No Beneficial Role in Heart Failure

ManchiniFront Physiol2017660nm

positiveRat

Maximal oxygen uptake and exercise tolerance are improved in rats with heart failure subjected to low-level laser therapy associated with resistance training.

HentschkeLasers Med Sci2016850nm

positiveRat

Acute effects of low-level laser therapy irradiation on blood lactate and muscle fatigue perception in hospitalized patients with heart failure-a pilot study.

BublitzLasers Med Sci2016808nm

positiveHuman

Light-emitting diode therapy (LEDT) improves functional capacity in rats with heart failure.

CapalongaLasers Med Sci2016850nm

positiveRat

Low-Level Laser Therapy to the Bone Marrow Reduces Scarring and Improves Heart Function Post-Acute Myocardial Infarction in the Pig.

BlattPhotomed Laser Surg2016808nm

positiveAnimal

Role of low-level laser therapy on the cardiac remodeling after myocardial infarction: A systematic review of experimental studies.

CarlosLife Sci2016

unclearReview

Low-Level Laser Irradiation Precondition for Cardiac Regenerative Therapy.

Liu & ZhangPhotomed Laser Surg2016

unclearReview

Method for Correction of Consequences of Radiation-Induced Heart Disease using Low-Intensity Electromagnetic Emission under Experimental Conditions.

BavrinaBull Exp Biol Med2015

positiveRat

Application of Low-Level Laser Therapy Following Coronary Artery Bypass Grafting (CABG) Surgery.

Kazemi KhooJ Lasers Med Sci2014810nm

positiveHuman

The influence of low-level laser therapy on parameters of oxidative stress and DNA damage on muscle and plasma in rats with heart failure.

BiasibettiLasers Med Sci2014660nm

positiveRat

Cardioprotection from ischemia-reperfusion injury by near-infrared light in rats.

QuirkPhotomed Laser Surg2014670nm

positiveRat

Blue LEDs get the Nobel Prize while Red LEDs are poised to save lives

Karam&AkarFront Physiol2014

unclearAnimal

Far red/near infrared light-induced protection against cardiac ischemia and reperfusion injury remains intact under diabetic conditions and is independent of nitric oxide synthase.

KeszlerFront Physiol2014670nm

positiveMouse

Amelioration of cardiac function and activation of anti-inflammatory vasoactive peptides expression in the rat myocardium by low level laser therapy.

ManchiniPLoS One2014660nm

positiveRat

Low-level laser therapy improves the inflammatory profile of rats with heart failure.

HentschkeLasers Med Sci2013660nm

positiveRat

Effect of low-level laser irradiation on oxygen free radicals and ventricular remodeling in the infarcted rat heart.

YangPhotomed Laser Surg2013635nm

positiveRat

Light-induced vasodilation of coronary arteries and its possible clinical implication.

PlassAnn Thorac Surg2012

positiveIn vitro

Low-level-laser irradiation induces photorelaxation in coronary arteries and overcomes vasospasm of internal thoracic arteries.

PlassLasers Surg Med2012680nm

positiveIn vitro

Low-level laser irradiation alters cardiac cytokine expression following acute myocardial infarction: a potential mechanism for laser therapy.

YangPhotomed Laser Surg2011635nm

positiveRat

Low-power light and isolated rat hearts after ischemia of myocardium.

MonichJ Photochem Photobiol B2011633nm

positiveRat

Induction of autologous mesenchymal stem cells in the bone marrow by low-level laser therapy has profound beneficial effects on the infarcted rat heart.

TubyLasers Surg Med2011804nm

positiveRat

Low level laser irradiation precondition to create friendly milieu of infarcted myocardium and enhance early survival of transplanted bone marrow cells.

ZhangJ Cell Mol Med2010804nm

positiveRat

Near infrared light protects cardiomyocytes from hypoxia and reoxygenation injury by a nitric oxide dependent mechanism.

ZhangJ Mol Cell Cardiol2009

positiveIn vitro

Enhancement of nitric oxide release from nitrosyl hemoglobin and nitrosyl myoglobin by red/near infrared radiation: potential role in cardioprotection.

LohrJ Mol Cell Cardiol2009670nm

positiveRabbit

Implantation of low-level laser irradiated mesenchymal stem cells into the infarcted rat heart is associated with reduction in infarct size and enhanced angiogenesis.

TubyPhotomed Laser Surg2009

positiveRat

Effect of low-intensity laser irradiation and wideband red light on experimentally ischemized myocardium.

MalinovskayaBull Exp Biol Med2008

positiveRat

Laser biostimulation in end-stage multivessel coronary artery disease--a preliminary observational study.

ZycińskiKardiol Pol2007633nm

positiveHuman

Effect of different LLLT on pituitrin-induced bradycardia in the rabbit.

ZhaoLasers Med Sci2006

positiveRabbit

Modulations of VEGF and iNOS in the rat heart by low level laser therapy are associated with cardioprotection and enhanced angiogenesis.

TubyLasers Surg Med2006804nm

positiveRat

It is time to test low level laser therapy in Great Britain.

Moshkovska & MayberryPostgrad Med J2005

unclearReview

Singlet oxygen energy illumination during moderate cold ischemia prolongs the survival of concordant hamster xeno-heart transplants.

LukesTransplant Proc2005634nm

positiveRat

Low-power Helium-Neon laser irradiation enhances the expression of VEGF in murine myocardium.

ZhangChin Med J (Engl)2004633nm

positiveRat

Long-term effect of low energy laser irradiation on infarction and reperfusion injury in the rat heart.

YaakobiLasers Surg Med2001804nm

positiveRat

Attenuation of infarct size in rats and dogs after myocardial infarction by low-energy laser irradiation.

OronLasers Surg Med2001

positiveRat

Low-energy laser irradiation reduces formation of scar tissue after myocardial infarction in rats and dogs.

OronCirculation2001803nm

positiveRat

Impact of low level laser irradiation on infarct size in the rat following myocardial infarction.

Ad & OronInt J Cardiol2001

positiveRat

Effects of red light on postischemic myocardium during reperfusion.

DrugovaBull Exp Biol Med2001

positiveRat

Ventricular remodeling after acute myocardial infarction: effect of low-intensity laser irradiation.

Whittaker & PattersonLasers Surg Med2000780nm

positiveRat

Recovery from sarafotoxin-b induced cardiopathological effects in mice following low energy laser irradiation.

YaakovBasic Res Cardiol2000

positiveMouse

Back to Full PBM Database

Related Products

Light Therapy Devices

FDA-cleared PBM devices, clinically reviewed

Continue Exploring

Sauna & Heat Therapy

1,945 studies

Cold Exposure

2,784 studies

Join the Discussion

Connect with others researching photobiomodulation. Share protocols, results, and questions.

How to Use This Site

Learn how products, research, protocols, and community connect across the platform.