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PBM Research167 studies

Photobiomodulation for Mechanisms

167 peer-reviewed studies on light therapy for mechanisms, spanning to 2020. Filtered from the full PBM database of 4,914 studies.

167

Total Studies

3

Human Studies

85

Positive Results

6

Wavelength Bands

Study Types

In vitro
75 (45%)
Review
70 (42%)
Animal
15 (9%)
Human
3 (2%)
Mouse
2 (1%)
Rat
2 (1%)

Outcomes

positive
85 (51%)
unclear
79 (47%)
negative
3 (2%)

Wavelength Distribution

Not specified

113 studies

Red (600-700nm)

40 studies

Near-IR (700-900nm)

6 studies

IR (900nm+)

5 studies

Green (500-600nm)

2 studies

Blue (<500nm)

1 studies

All Studies (167)

Mitochondrial solar sensitivity: evolutionary and biomedical implications.

Sommer APAnn Transl Med2020
unclearReview

Quantum biology in low level light therapy: death of a dogma.

SommerAnn Transl Med2020
unclearReview

Light-induced modulation of the mitochondrial respiratory chain activity: possibilities and limitations.

LunovaCell Mol Life Sci2019
positiveIn vitro

A day in the life of mitochondria reveals shifting workloads.

WeinrichSci Rep2019670nm
positiveAnimal

1064 nm Nd:YAG laser light affect transmembrane mitochondria respiratory chain complexes.

RaveraJ Biophotonics2019
positiveIn vitro

Photobiomodulation enhancement of cell proliferation at 660 nm does not require cytochrome c oxidase.

LimaJ Photochem Photobiol B2019660nm
negativeIn vitro

Red and near-infrared light induces intracellular Ca2+ flux via the activation of glutamate N-methyl-D-aspartate receptors.

GolovynskaJ Cell Physiol.2019
positiveIn vitro

Differential Responses of Myoblasts and Myotubes to Photobiomodulation are associated with Mitochondrial Number.

SerrageJ Biophotonics2019
positiveIn vitro

The Influence of Light on Reactive Oxygen Species and NF-кB in Disease Progression.

Kumar RajendranAntioxidants (Basel)2019
unclearReview

Mitochondrial cytochrome c oxidase is not the primary acceptor for near infrared light-it is mitochondrial bound water: the principles of low-level light therapy.

Sommer APAnn Transl Med2019
unclearReview

Revisiting the Photon/Cell Interaction Mechanism in Low-Level Light Therapy

Sommer APPhotobiomodul Photomed Laser Surg2019
unclearReview

Use of Exogenous and Endogenous Photomediators as Efficient ROS Modulation Tools: Results and Perspectives for Therapeutic Purposes.

AntognazzaOxid Med Cell Longev2019
unclearReview

Effect of Low-Level Laser Irradiation on the Function of Glycated Catalase.

MirmiranpourJ Lasers Med Sci2018
positiveIn vitro

Is Photodynamic Therapy Resistance a Special Case of Photobiomodulation?

QuirkPhotomed Laser Surg2018
unclearAnimal

Photobiomodulation in Light of Our Biological Clock's Inner Workings.

Santana-Blank & Rodríguez-SantanaPhotomed Laser Surg2018
unclearAnimal

Photoactivation of cytochrome c-oxidase activity of mitochondria of the liver of Japanese quail with therapeutic doses of blue and red LED irradiation [Russian article]

DontsovPathological Physiology and Experimental Therapy [title translated from Russian]2018
positiveIn vitro

Red light-emitting diode irradiation regulates oxidative stress and inflammation through SPHK1/NF-κB activation in human keratinocytes.

SunJ Photochem Photobiol B2018
positiveIn vitro

Photobiomodulation with red light emitting diodes accelerates hepatocytes proliferation through reactive oxygen species /extracellular signal-regulated kinase pathway.

FengHepatol Res2018635nm
positiveIn vitro

Manipulating the mitochondria activity in human hepatic cell line Huh7 by low-power laser irradiation.

LynnykBiomed Opt Express2018655nm
positiveIn vitro

Impact of heat on metabolic and hemodynamic changes in transcranial infrared laser stimulation measured by broadband near-infrared spectroscopy.

WangNeurophotonics20181064nm
positiveHuman

Photobiomodulation Affects Key Cellular Pathways of all Life-forms: Considerations on Old and New Laser Light-targets and the Calcium Issue.

AmaroliPhotochem Photobiol2018
unclearReview

Non-mammalian Hosts and Photobiomodulation: Do All Life-forms Respond to Light?

HamblinPhotochem Photobiol2018
unclearReview

Near infrared low level laser therapy and cell proliferation: the emerging role of redox sensitive signal transduction pathways.

MigliarioJ Biophotonics2018
unclearReview

Mechanisms and Mitochondrial Redox Signaling in Photobiomodulation.

Hamblin MRPhotochem Photobiol2018
unclearReview

Photobiomodulation Therapy Improves Acute Inflammatory Response in Mice: the Role of Cannabinoid Receptors/ATP-Sensitive K+ Channel/p38-MAPK Signalling Pathway.

NevesMol Neurobiol2017660nm
positiveMouse

Photobiomodulation of human dermal fibroblasts in vitro: decisive role of cell culture conditions and treatment protocols on experimental outcome.

MignonSci Rep2017
positiveIn vitro

Up-regulation of cerebral cytochrome-c-oxidase and hemodynamics by transcranial infrared laser stimulation: A broadband near-infrared spectroscopy study.

WangJ Cereb Blood Flow Metab20171064nm
positiveHuman

Mechanisms and applications of the anti-inflammatory effects of photobiomodulation

Hamblin MRAIMS Biophysics2017
unclearReview

Remote tissue conditioning - an emerging approach for inducing body-wide protection against diseases of ageing.

KimAgeing Res Rev2017
unclearReview

Interplay between up-regulation of cytochrome-c-oxidase and hemoglobin oxygenation induced by near-infrared laser.

WangSci Rep2016
positiveHuman

An 808-nm Diode Laser with a Flat-Top Handpiece Positively Photobiomodulates Mitochondria Activities.

AmaroliPhotomed Laser Surg2016
negativeIn vitro

Photobiomodulation of human adipose-derived stem cells using 810nm and 980nm lasers operates via different mechanisms of action.

WangBiochim Biophys Acta2016
positiveIn vitro

Laser-activated transforming growth factor-β1 induces human β-defensin 2: implications for laser therapies for periodontitis and peri-implantitis.

TangJ Periodontal Res2016810nm
positiveIn vitro

Effect of Red-to-Near Infrared Light on the Reaction of Isolated Cytochrome c Oxidase with Cytochrome c.

Quirk & WhelanPhotomed Laser Surg2016
positiveIn vitro

Proposed Mechanisms of Photobiomodulation or Low-Level Light Therapy

Freitas & HamblinIEEE J Sel Top Quantum Electron2016
unclearReview

Craniofacial Wound Healing with Photobiomodulation Therapy: New Insights and Current Challenges.

Arany PRJ Dent Res2016
unclearReview

Stimulation of Cellular Proliferation and Migration: Is It a Viable Measure of Photobiomodulation?

Abrahamse HPhotomed Laser Surg2015
unclearAnimal

Measuring the dynamics of cyclic adenosine monophosphate level in living cells induced by low-level laser irradiation using bioluminescence resonance energy transfer.

HuangJ Biomed Opt2015
positiveIn vitro

A mechanism for ultrasound/light-induced biostimulation.

Sommer APAnn Transl Med2015
unclearReview

Tuning the mitochondrial rotary motor with light.

Sommer APAnn Transl Med2015
unclearReview

Red light as a 12-oxo-leukotriene B₄ antagonist: an explanation for the efficacy of intensive red light in the therapy of peripheral inflammatory diseases.

PaschkeBiomed Tech (Berl)2014632nm
positiveAnimal

Effects of low-level laser therapy on mitochondrial respiration and nitrosyl complex content.

BuravlevLasers Med Sci2014442nm
positiveIn vitro

Photobiomodulation on KATP Channels of Kir6.2-Transfected HEK-293 Cells

ZhongInt J Photoenergy2014808nm
positiveIn vitro

Absorption of monochromatic and narrow band radiation in the visible and near IR by both mitochondrial and non-mitochondrial photoacceptors results in photobiomodulation.

Passarella & KaruJ Photochem Photobiol B2014
unclearReview

Lightening up Light Therapy: Activation of Retrograde Signaling Pathway by Photobiomodulation

Hong P KimBiomol Ther (Seoul)2014
unclearReview

Biological effects of low level laser therapy.

FarivarJ Lasers Med Sci2014
unclearReview

Pre-conditioning with low-level laser (light) therapy: light before the storm.

AgrawalDose Response2014
unclearReview

Effects of laser and LED radiation on mitochondrial respiration in experimental endotoxic shock.

BuravlevLasers Med Sci2013
positiveRat

Photobiomodulation of aqueous interfaces: finding evidence to support the exclusion zone in experimental and clinical studies.

Santana-BlankPhotomed Laser Surg2013
unclearAnimal

Intracellular signaling cascades following light irradiation

Wu & XingLaser Photon Rev2013
unclearReview
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