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PBM Research168 studies

Photobiomodulation for Nervous system

168 peer-reviewed studies on light therapy for nervous system, spanning 1978 to 2020. Filtered from the full PBM database of 4,914 studies.

168

Total Studies

45

Human Studies

137

Positive Results

4

Wavelength Bands

Study Types

Rat
71 (42%)
Human
45 (27%)
Review
18 (11%)
In vitro
13 (8%)
Animal
8 (5%)
Rabbit
6 (4%)

Outcomes

positive
137 (82%)
unclear
25 (15%)
negative
6 (4%)

Wavelength Distribution

Near-IR (700-900nm)

60 studies

Not specified

58 studies

Red (600-700nm)

37 studies

IR (900nm+)

13 studies

All Studies (168)

Photobiomodulation After Neurotization (Oberlin Procedure) in Brachial Plexus Injury: A Randomized Control Trial.

FooPhotobiomodul Photomed Laser Surg2020808nm
positiveHuman

Efficacy of low-level laser therapy on management of Bell's palsy: a systematic review.

JavaherianLasers Med Sci2020
unclearReview

Complete and Fast Recovery from Idiopathic Facial Paralysis Using Laser-Photobiomodulation.

TanganeliCase Rep Dent2020808nm
positiveHuman

The efficiency of ozone therapy and low-level laser therapy in rat facial nerve injury.

YucaJ Craniomaxillofac Surg2020850nm
positiveRat

Retrospective Observational Study and Analysis of Two Different Photobiomodulation Therapy Protocols Combined with Rehabilitation Therapy as Therapeutic Interventions for Canine Degenerative Myelopathy.

MillerPhotobiomodul Photomed Laser Surg2020
positiveAnimal

Effect of Modified Laser Transcutaneous Irradiation on Pain and Quality of Life in Patients with Diabetic Neuropathy.

da Silva LealPhotobiomodul Photomed Laser Surg2020660nm
positiveHuman

Low-Level Laser Effect on Peripheral Sciatic Regeneration Under the Systemic Inflammatory Condition of Periodontal Disease.

MalanotteJ Lasers Med Sci2020830nm
positiveOther

Dose-dependent effect of the pulsed Nd:YAG laser in the treatment of crushed sciatic nerve in Wister rats: an experimental model.

AlayatLasers Med Sci20201064nm
positiveRat

Sensory and motor responses after photobiomodulation associated with physiotherapy in patients with incomplete spinal cord injury: clinical, randomized trial.

da SilvaLasers Med Sci2020808nm
positiveHuman

Efficacy of laser acupuncture for patients with chronic Bell's palsy: A study protocol for a randomized, double-blind, sham-controlled pilot trial.

TonMedicine (Baltimore)2019
unclearAnimal

Sensory-motor and cardiorespiratory sensory rehabilitation associated with transcranial photobiomodulation in patients with central nervous system injury: Trial protocol for a single-center, randomized, double-blind, and controlled clinical trial.

PintoMedicine (Baltimore)2019
unclearAnimal

Effect of Low Level Laser Therapy on serum vitamin D and magnesium levels in patients with diabetic peripheral neuropathy - A pilot study.

AnjuDiabetes Metab Syndr2019
positiveHuman

Low level laser therapy for the patients with painful diabetic peripheral neuropathy - A systematic review

AnjuDiabetes & Metabolic Syndrome: Clinical Research & Reviews2019
unclearReview

Photobiomodulation therapy at different wavelength impacts on retinoid acid-dependent SH-SY5Y differentiation.

LuisaLasers Med Sci2019
positiveIn vitro

Use of low-power He-Ne laser therapy to accelerate regeneration processes of injured sciatic nerve in rabbit.

Al-ShammariEgypt J Neurol Psychiatr Neurosurg2019633nm
positiveRabbit

Growth factors expression and ultrastructural morphology after application of low-level laser and natural latex protein on a sciatic nerve crush-type injury.

DiasPLoS One2019780nm
positiveRat

Photobiomodulation By Diffusing Optical Fiber on Spinal Cord:A Feasibility Study in piglet model.

LiangJ Biophotonics2019810nm
positiveAnimal

The effect of 808 nm and 905 nm wavelength light on recovery after spinal cord injury.

SvobodovaSci Rep2019
positiveRat

Photobiomodulation Therapy Inhibit the Activation and Secretory of Astrocytes by Altering Macrophage Polarization.

SunCell Mol Neurobiol2019
positiveMouse

Co-administration of human adipose-derived stem cells and low-level laser to alleviate neuropathic pain after experimental spinal cord injury.

SarveazadStem Cell Res Ther2019660nm
positiveRat

Bell's palsy treated with photobiomodulation in an adolescent: Rare case report and review of the published literature

PoloniInt J Paediatr Dent2018830nm
positiveHuman

Photobiomodulation induces antinociception, recovers structural aspects and regulates mitochondrial homeostasis in peripheral nerve of diabetic mice.

da Silva de OliveiraJ Biophotonics2018660nm
positiveMouse

Efficiencies of Low-Level Laser Therapy (LLLT) and Gabapentin in the Management of Peripheral Neuropathy: Diabetic Neuropathy.

Abdel-WahhabAppl Biochem Biotechnol2018808nm
positiveRat

Effects of Photobiomodulation on Functionality in Wistar Rats with Sciatic Nerve Injury.

AndreoPhotochem Photobiol2018780nm
unclearRat

Biochemical changes in injured sciatic nerve of rats after low-level laser therapy (660 nm and 808 nm) evaluated by Raman spectroscopy.

de Almeida Melo Maciel MangueiraLasers Med Sci2018
positiveRat

Low Level Laser Therapy for Radial Nerve Palsy Patients : Our Experience.

OshimaLaser Ther2018830nm
positiveHuman

Photobiomodulation Therapy (PBMT) in Peripheral Nerve Regeneration: A Systematic Review.

RossoBioengineering (Basel)2018
unclearReview

Comparative effect of photobiomodulation associated with dexamethasone after sciatic nerve injury model.

de SouzaLasers Med Sci2018660nm
positiveMouse

Therapeutic effects of simultaneous Photobiomodulation therapy (PBMT) and Meloxicam administration on experimental acute spinal cord injury: Rat animal model.

PedramJ Photochem Photobiol B2018810nm
positiveRat

Photobiomodulation improves motor response in patients with spinal cord injury submitted to electromyographic evaluation: randomized clinical trial.

da SilvaLasers Med Sci2018808nm
positiveHuman

Role of low-level laser therapy added to facial expression exercises in patients with idiopathic facial (Bell's) palsy.

Ordahan & KarahanLasers Med Sci2017830nm
positiveHuman

Stimulation of morphofunctional repair of the facial nerve with photobiomodulation, using the end-to-side technique or a new heterologous fibrin sealant.

RossoJ Photochem Photobiol B2017830nm
positiveRat

Efficacy of Laser Photobiomodulation on Morphological and Functional Repair of the Facial Nerve.

BuchaimPhotomed Laser Surg2017830nm
positiveRat

Clinical effectiveness of low-level laser treatment on peripheral somatosensory neuropathy.

FallahLasers Med Sci2017
unclearReview

Effects of monochromatic infrared phototherapy in patients with diabetic peripheral neuropathy: a systematic review and meta-analysis of randomized controlled trials.

RobinsonBraz J Phys Ther2017
unclearReview

Infrared neural stimulation induces intracellular Ca2+ release mediated by phospholipase C.

MoreauJ Biophotonics20171470nm
positiveIn vitro

Effects of photobiomodulation on experimental models of peripheral nerve injury.

AndreoLasers Med Sci2017
unclearReview

Stimulation Effect of Low Level Laser Therapy on Sciatic Nerve Regeneration in Rat.

Mashhoudi BarezJ Lasers Med Sci2017780nm
positiveRat

LLLT actives MMP-2 and increases muscle mechanical resistance after nerve sciatic rat regeneration.

AndrausLasers Med Sci2017830nm
positiveRat

Clinical effectiveness of low-level laser treatment on peripheral somatosensory neuropathy.

FallahLasers Med Sci2017
unclearReview

Analysis of the variation in low-level laser energy density on the crushed sciatic nerves of rats: a morphological, quantitative, and morphometric study.

ZiagoLasers Med Sci2017780nm
positiveRat

Photobiomodulation in Neuroscience: A Summary of Personal Experience.

RochkindPhotomed Laser Surg2017
unclearReview

Beyond the Laboratory, Into the Clinic: What Dogs with Disk Disease Have Taught Us About Photobiomodulation for Spinal Cord Injury.

RobinsonPhotomed Laser Surg2017
unclearReview

Combine effect of Chondroitinase ABC and low level laser (660nm) on spinal cord injury model in adult male rats.

JanzadehNeuropeptides2017660nm
positiveRat

The role of low level laser therapy on neuropathic pain relief and interleukin-6 expression following spinal cord injury; an experimental study.

MojaradJ Chem Neuroanat2017660nm
positiveRat

Low-level laser facilitates alternatively activated macrophage/microglia polarization and promotes functional recovery after crush spinal cord injury in rats.

SongSci Rep2017810nm
positiveRat

Effects of different fluences of low-level laser therapy in an experimental model of spinal cord injury in rats.

VeronezLasers Med Sci2017808nm
positiveRat

Comparative assessment of phototherapy protocols for reduction of oxidative stress in partially transected spinal cord slices undergoing secondary degeneration.

AshworthBMC Neurosci2016
positiveIn vitro

The new heterologous fibrin sealant in combination with low-level laser therapy (LLLT) in the repair of the buccal branch of the facial nerve.

BuchaimLasers Med Sci2016830nm
positiveRat

GaAs laser therapy reestablishes the morphology of the NMJ and nAChRs after injury due to bupivacaine

PissulinJ Photochem Photobiol B2016904nm
positiveRat
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